Pesquisa | BVS IEC

1.

Novel breast cancer susceptibility loci under linkage peaks identified in African ancestry consortia.

Ochs-Balcom, Heather M; Preus, Leah; Du, Zhaohui; Elston, Robert C; Teerlink, Craig C; Jia, Guochong; Guo, Xingyi; Cai, Qiuyin; Long, Jirong; Ping, Jie; Li, Bingshan; Stram, Daniel O; Shu, Xiao-Ou; Sanderson, Maureen; Gao, Guimin; Ahearn, Thomas; Lunetta, Kathryn L; Zirpoli, Gary; Troester, Melissa A; Ruiz-Narváez, Edward A; Haddad, Stephen A; Figueroa, Jonine; John, Esther M; Bernstein, Leslie; Hu, Jennifer J; Ziegler, Regina G; Nyante, Sarah; Bandera, Elisa V; Ingles, Sue A; Mancuso, Nicholas; Press, Michael F; Deming, Sandra L; Rodriguez-Gil, Jorge L; Yao, Song; Ogundiran, Temidayo O; Ojengbede, Oladosu; Bolla, Manjeet K; Dennis, Joe; Dunning, Alison M; Easton, Douglas F; Michailidou, Kyriaki; Pharoah, Paul D P; Sandler, Dale P; Taylor, Jack A; Wang, Qin; O'Brien, Katie M; Weinberg, Clarice R; Kitahara, Cari M; Blot, William; Nathanson, Katherine L.

Hum Mol Genet ; 33(8): 687-697, 2024 Apr 08.

Artigo em Inglês | MEDLINE | ID: mdl-38263910

2.

Efficacy and Safety of Bepirovirsen in Chronic Hepatitis B Infection.

Yuen, Man-Fung; Lim, Seng-Gee; Plesniak, Robert; Tsuji, Keiji; Janssen, Harry L A; Pojoga, Cristina; Gadano, Adrian; Popescu, Corneliu P; Stepanova, Tatyana; Asselah, Tarik; Diaconescu, Gheorghe; Yim, Hyung Joon; Heo, Jeong; Janczewska, Ewa; Wong, Alexander; Idriz, Nevin; Imamura, Michio; Rizzardini, Giuliano; Takaguchi, Koichi; Andreone, Pietro; Arbune, Manuela; Hou, Jinlin; Park, Sung Jae; Vata, Andrei; Cremer, Jennifer; Elston, Robert; Lukic, Tamara; Quinn, Geoff; Maynard, Lauren; Kendrick, Stuart; Plein, Helene; Campbell, Fiona; Paff, Melanie; Theodore, Dickens.

N Engl J Med ; 387(21): 1957-1968, 2022 11 24.

Artigo em Inglês | MEDLINE | ID: mdl-36346079

3.

An Accidental Genetic Epidemiologist.

Elston, Robert C.

Annu Rev Genomics Hum Genet ; 21: 15-36, 2020 08 31.

Artigo em Inglês | MEDLINE | ID: mdl-31935127

4.

Comparison of Pharmacokinetics of the GalNAc-Conjugated Antisense Oligonucleotide GSK3389404 in Participants with Chronic Hepatitis B Infection across the Asia-Pacific Region.

Han, Kelong; Ito, Hiroshi; Elston, Robert; Cremer, Jennifer; Hood, Steve; Paff, Melanie; Theodore, Dickens.

Antimicrob Agents Chemother ; 67(1): e0090022, 2023 01 24.

Artigo em Inglês | MEDLINE | ID: mdl-36507675

5.

Phase IIa, randomised, double-blind study of GSK3389404 in patients with chronic hepatitis B on stable nucleos(t)ide therapy.

Yuen, Man-Fung; Heo, Jeong; Kumada, Hiromitsu; Suzuki, Fumitaka; Suzuki, Yoshiyuki; Xie, Qing; Jia, Jidong; Karino, Yoshiyasu; Hou, Jinlin; Chayama, Kazuaki; Imamura, Michio; Lao-Tan, Judy Y; Lim, Seng Gee; Tanaka, Yasuhito; Xie, Wen; Yoon, Jung-Hwan; Duan, Zhongping; Kurosaki, Masayuki; Park, Sung-Jae; Labio, Madalinee Eternity; Kumar, Rajneesh; Kweon, Young-Oh; Yim, Hyung Joon; Tao, Yu; Cremer, Jennifer; Elston, Robert; Davies, Matt; Baptiste-Brown, Sharon; Han, Kelong; Campbell, Fiona M; Paff, Melanie; Theodore, Dickens.

J Hepatol ; 77(4): 967-977, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-35714812

6.

Efficacy and Safety of Bepirovirsen in Hepatitis B. Reply.

Yuen, Man-Fung; Elston, Robert; Theodore, Dickens.

N Engl J Med ; 388(12): 1147-1148, 2023 Mar 23.

Artigo em Inglês | MEDLINE | ID: mdl-36947478

7.

Fisher's influence on me.

Elston, Robert C.

Genet Epidemiol ; 42(8): 849-853, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30298598

8.

Adjustment for covariates using summary statistics of genome-wide association studies.

Wang, Tao; Xue, Xiaonan; Xie, Xianhong; Ye, Kenny; Zhu, Xiaofeng; Elston, Robert C.

Genet Epidemiol ; 42(8): 812-825, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30238496

9.

ONETOOL for the analysis of family-based big data.

Song, Yeunjoo E; Lee, Sungyoung; Park, Kyungtaek; Elston, Robert C; Yang, Hyeon-Jong; Won, Sungho.

Bioinformatics ; 34(16): 2851-2853, 2018 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-29596615

10.

Applying family analyses to electronic health records to facilitate genetic research.

Huang, Xiayuan; Elston, Robert C; Rosa, Guilherme J; Mayer, John; Ye, Zhan; Kitchner, Terrie; Brilliant, Murray H; Page, David; Hebbring, Scott J.

Bioinformatics ; 34(4): 635-642, 2018 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-28968884

11.

Reply to: "Bepirovirsen/GSK3389404: Antisense or TLR9 agonists?"

You, Shihyun; Elston, Robert; Yuen, Man-Fung.

J Hepatol ; 78(3): e108-e110, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36460165

12.

How Consistent are Genetic Factors in Explaining Leisure-Time Physical Activity and Sport Participation? The Portuguese Healthy Families Study.

Pereira, Sara; Katzmarzyk, Peter T; Gomes, Thayse N; Elston, Robert; Maia, José.

Twin Res Hum Genet ; 21(5): 369-377, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-29976260

13.

Novel recurrently mutated genes in African American colon cancers.

Guda, Kishore; Veigl, Martina L; Varadan, Vinay; Nosrati, Arman; Ravi, Lakshmeswari; Lutterbaugh, James; Beard, Lydia; Willson, James K V; Sedwick, W David; Wang, Zhenghe John; Molyneaux, Neil; Miron, Alexander; Adams, Mark D; Elston, Robert C; Markowitz, Sanford D; Willis, Joseph E.

Proc Natl Acad Sci U S A ; 112(4): 1149-54, 2015 Jan 27.

Artigo em Inglês | MEDLINE | ID: mdl-25583493

14.

Molecular Basis of Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS Gene-Gene Interaction Involved in Atrial Fibrillation.

Huang, Yufeng; Wang, Chuchu; Yao, Yufeng; Zuo, Xiaoyu; Chen, Shanshan; Xu, Chengqi; Zhang, Hongfu; Lu, Qiulun; Chang, Le; Wang, Fan; Wang, Pengxia; Zhang, Rongfeng; Hu, Zhenkun; Song, Qixue; Yang, Xiaowei; Li, Cong; Li, Sisi; Zhao, Yuanyuan; Yang, Qin; Yin, Dan; Wang, Xiaojing; Si, Wenxia; Li, Xiuchun; Xiong, Xin; Wang, Dan; Huang, Yuan; Luo, Chunyan; Li, Jia; Wang, Jingjing; Chen, Jing; Wang, Longfei; Wang, Li; Han, Meng; Ye, Jian; Chen, Feifei; Liu, Jingqiu; Liu, Ying; Wu, Gang; Yang, Bo; Cheng, Xiang; Liao, Yuhua; Wu, Yanxia; Ke, Tie; Chen, Qiuyun; Tu, Xin; Elston, Robert; Rao, Shaoqi; Yang, Yanzong; Xia, Yunlong; Wang, Qing K.

PLoS Genet ; 11(8): e1005393, 2015 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-26267381

15.

Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).

Iyengar, Sudha K; Sedor, John R; Freedman, Barry I; Kao, W H Linda; Kretzler, Matthias; Keller, Benjamin J; Abboud, Hanna E; Adler, Sharon G; Best, Lyle G; Bowden, Donald W; Burlock, Allison; Chen, Yii-Der Ida; Cole, Shelley A; Comeau, Mary E; Curtis, Jeffrey M; Divers, Jasmin; Drechsler, Christiane; Duggirala, Ravi; Elston, Robert C; Guo, Xiuqing; Huang, Huateng; Hoffmann, Michael Marcus; Howard, Barbara V; Ipp, Eli; Kimmel, Paul L; Klag, Michael J; Knowler, William C; Kohn, Orly F; Leak, Tennille S; Leehey, David J; Li, Man; Malhotra, Alka; März, Winfried; Nair, Viji; Nelson, Robert G; Nicholas, Susanne B; O'Brien, Stephen J; Pahl, Madeleine V; Parekh, Rulan S; Pezzolesi, Marcus G; Rasooly, Rebekah S; Rotimi, Charles N; Rotter, Jerome I; Schelling, Jeffrey R; Seldin, Michael F; Shah, Vallabh O; Smiles, Adam M; Smith, Michael W; Taylor, Kent D; Thameem, Farook.

PLoS Genet ; 11(8): e1005352, 2015 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-26305897

16.

On the association analysis of CNV data: a fast and robust family-based association method.

Liu, Meiling; Moon, Sanghoon; Wang, Longfei; Kim, Sulgi; Kim, Yeon-Jung; Hwang, Mi Yeong; Kim, Young Jin; Elston, Robert C; Kim, Bong-Jo; Won, Sungho.

BMC Bioinformatics ; 18(1): 217, 2017 Apr 18.

Artigo em Inglês | MEDLINE | ID: mdl-28420343

17.

Family-Based Rare Variant Association Analysis: A Fast and Efficient Method of Multivariate Phenotype Association Analysis.

Wang, Longfei; Lee, Sungyoung; Gim, Jungsoo; Qiao, Dandi; Cho, Michael; Elston, Robert C; Silverman, Edwin K; Won, Sungho.

Genet Epidemiol ; 40(6): 502-11, 2016 09.

Artigo em Inglês | MEDLINE | ID: mdl-27312886

18.

The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function.

Wang, Ya-Juan; Tayo, Bamidele O; Bandyopadhyay, Anupam; Wang, Heming; Feng, Tao; Franceschini, Nora; Tang, Hua; Gao, Jianmin; Sung, Yun Ju; Elston, Robert C; Williams, Scott M; Cooper, Richard S; Mu, Ting-Wei; Zhu, Xiaofeng.

PLoS Genet ; 10(9): e1004641, 2014 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-25233454

19.

Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND).

Williams, Robert C; Elston, Robert C; Kumar, Pankaj; Knowler, William C; Abboud, Hanna E; Adler, Sharon; Bowden, Donald W; Divers, Jasmin; Freedman, Barry I; Igo, Robert P; Ipp, Eli; Iyengar, Sudha K; Kimmel, Paul L; Klag, Michael J; Kohn, Orly; Langefeld, Carl D; Leehey, David J; Nelson, Robert G; Nicholas, Susanne B; Pahl, Madeleine V; Parekh, Rulan S; Rotter, Jerome I; Schelling, Jeffrey R; Sedor, John R; Shah, Vallabh O; Smith, Michael W; Taylor, Kent D; Thameem, Farook; Thornley-Brown, Denyse; Winkler, Cheryl A; Guo, Xiuqing; Zager, Phillip; Hanson, Robert L.

BMC Genomics ; 17: 325, 2016 05 04.

Artigo em Inglês | MEDLINE | ID: mdl-27142425

20.

Immunoglobulin G genotypes and the risk of schizophrenia.

Pandey, Janardan P; Namboodiri, Aryan M; Elston, Robert C.

Hum Genet ; 135(10): 1175-9, 2016 10.

Artigo em Inglês | MEDLINE | ID: mdl-27393575

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Instituto Evandro Chagas

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